Involvement of c-Fos in cell proliferation, migration, and invasion in osteosarcoma cells accompanied by altered expression of Wnt2 and Fzd9.

Osteosarcoma (OS) is an aggressive bone tumor, and proto-oncogene c-Fos is involved in this lethal disease. However, the role and molecular mechanism of c-Fos in the development and progression of OS remain enigmatic. As one of the Wnt family members, Wnt2 is closely associated with the development...

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Bibliographic Details
Main Authors: Qiaozhen Wang, Huancai Liu, Qing Wang, Fenghua Zhou, Yongxin Liu, Yawen Zhang, Haoyu Ding, Meng Yuan, Fengjie Li, Yanchun Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5493424?pdf=render