Macrophages induce CD47 upregulation via IL-6 and correlate with poor survival in hepatocellular carcinoma patients

CD47 is known to be involved in phagocyte-mediated tumor clearance; however, its expression, clinical significance, and regulatory mechanism in hepatocellular carcinoma (HCC) remain poorly understood. In the present study, we found that upregulation of CD47 expression on tumor cells was correlated w...

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Bibliographic Details
Main Authors: Jing Chen, Dan-Xue Zheng, Xing-Juan Yu, Hong-Wei Sun, Yi-Tuo Xu, Yao-Jun Zhang, Jing Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2019-11-01
Series:OncoImmunology
Subjects:
hcc
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1652540