Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's disease

Mitochondrial oxidative stress and dysfunction has been implicated as a possible mechanism for the onset and progression of Parkinson-like neurodegeneration. However, long-term mitochondrial defects in chronic animal neurodegenerative models have not been demonstrated. In this study, we investigated...

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Bibliographic Details
Main Authors: Gaurav Patki, Yi Che, Yuen-Sum Lau
Format: Article
Language:English
Published: Frontiers Media S.A. 2009-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/neuro.24.003.2009/full