3D Biomimetic Scaffold for Growth Factor Controlled Delivery: An In-Vitro Study of Tenogenic Events on Wharton’s Jelly Mesenchymal Stem Cells

3D Biomimetic Scaffold for Growth Factor Controlled Delivery: An In-Vitro Study of Tenogenic Events on Wharton’s Jelly Mesenchymal Stem Cells

The present work described a bio-functionalized 3D fibrous construct, as an interactive teno-inductive graft model to study tenogenic potential events of human mesenchymal stem cells collected from Wharton’s Jelly (hWJ-MSCs). The 3D-biomimetic and bioresorbable scaffold was functionalized with nanoc...

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Bibliographic Details
Main Authors: Maria Camilla Ciardulli, Joseph Lovecchio, Pasqualina Scala, Erwin Pavel Lamparelli, Tina Patricia Dale, Valentina Giudice, Emanuele Giordano, Carmine Selleri, Nicholas Robert Forsyth, Nicola Maffulli, Giovanna Della Porta
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceutics
Subjects:
human Wharton’s Jelly Mesenchymal Stem Cells
hGDF-5 controlled delivery
PLGA nanocarriers
3D fibrin scaffold
tenogenic commitment
cyclic strain bioreactor systems
Online Access:https://www.mdpi.com/1999-4923/13/9/1448

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https://www.mdpi.com/1999-4923/13/9/1448

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