Comprehensive analysis of tumour mutational burden and its clinical significance in prostate cancer
Abstract Background The tumorigenesis of prostate cancer involves genetic mutations. Tumour mutational burden (TMB) is an emerging biomarker for predicting the efficacy of immunotherapy. Results Single-nucleotide polymorphisms were the most common variant type, and C>T transversion was the most c...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-02-01
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| Series: | BMC Urology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12894-021-00795-7 |