Cellular Prion Protein: From Physiology to Pathology

The human cellular prion protein (PrPC) is a glycosylphosphatidylinositol (GPI) anchored membrane glycoprotein with two N-glycosylation sites at residues 181 and 197. This protein migrates in several bands by Western blot analysis (WB). Interestingly, PNGase F treatment of human brain homogenates pr...

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Bibliographic Details
Main Authors: Yutaka Kikuchi, José B. Oliveira-Martins, Yoshiko Sugita-Konishi, Sei-ichi Yusa
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Viruses
Subjects:
C1
Online Access:http://www.mdpi.com/1999-4915/4/11/3109