Mathematical modeling of intraplaque neovascularization and hemorrhage in a carotid atherosclerotic plaque

Abstract Background Growing experimental evidence has identified neovascularization from the adventitial vasa vasorum and induced intraplaque hemorrhage (IPH) as critical indicators during the development of vulnerable atherosclerotic plaques. In this study, we propose a mathematical model incorpora...

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Bibliographic Details
Main Authors: Yan Cai, Jichao Pan, Zhiyong Li
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BioMedical Engineering OnLine
Subjects:
Online Access:https://doi.org/10.1186/s12938-021-00878-4