Plasmodium falciparum VAR2CSA-Specific IgG Subclass Responses Reflect Protection Against Low Birth Weight and Pregnancy-Associated Malaria

Plasmodium falciparum VAR2CSA-Specific IgG Subclass Responses Reflect Protection Against Low Birth Weight and Pregnancy-Associated Malaria

Sequestration of Plasmodium falciparum-infected erythrocytes expressing the VAR2CSA antigen in the placenta results in poor pregnancy outcomes, including low birth weight and maternal anemia. Antigen-specific antibody-mediated immunity is acquired during successive pregnancies. Thus, evaluating VAR2...

Full description

Bibliographic Details
Main Authors: Bernard Tornyigah, Tania d’Almeida, Guillaume Escriou, Firmine Viwami, Nadine Fievet, Adrian J. F. Luty, Achille Massougbodji, Morten A. Nielsen, Philippe Deloron, Nicaise Tuikue Ndam
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
pregnancy
malaria
VAR2CSA
IgG subclasses
IgG3
IgG4
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.610305/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.610305/full

Similar Items