Predominance of Heart Failure With Preserved Ejection Fraction in Postmenopausal Women: Intra- and Extra-Cardiomyocyte Maladaptive Alterations Scaffolded by Estrogen Deficiency

Predominance of Heart Failure With Preserved Ejection Fraction in Postmenopausal Women: Intra- and Extra-Cardiomyocyte Maladaptive Alterations Scaffolded by Estrogen Deficiency

Heart failure (HF) remains a public health concern as it is associated with high morbidity and death rates. In particular, heart failure with preserved ejection fraction (HFpEF) represents the dominant (>50%) form of HF and mostly occurring among postmenopausal women. Hence, the initiation an...

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Bibliographic Details
Main Authors: Adebayo Oluwafemi Adekunle, Gabriel Komla Adzika, Richard Mprah, Marie Louise Ndzie Noah, Joseph Adu-Amankwaah, Ruqayya Rizvi, Nazma Akhter, Hong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
HFpEF
estrogen deficiency
β-adrenergic receptors
calcium handling
cardiomyocyte cytoskeleton
extra cellular matrix
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.685996/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.685996/full

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