Cearoin Induces Autophagy, ERK Activation and Apoptosis via ROS Generation in SH-SY5Y Neuroblastoma Cells

Neuroblastomas are the most common solid extracranial tumors in childhood. We investigated the anticancer effect of cearoin isolated from Dalbergia odorifera in human neuroblastoma SH-SY5Y cells. SH-SY5Y cells were treated with various doses of cearoin. The viability was measured by MTT assay. DCFDA...

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Bibliographic Details
Main Authors: Tonking Bastola, Ren-bo An, Youn-Chul Kim, Jaehyo Kim, Jungwon Seo
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Molecules
Subjects:
ERK
Online Access:http://www.mdpi.com/1420-3049/22/2/242