RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development.

RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development.

The Pam/Highwire/RPM-1 (PHR) proteins are key regulators of neuronal development that function in axon extension and guidance, termination of axon outgrowth, and synapse formation. Outside of development, the PHR proteins also regulate axon regeneration and Wallerian degeneration. The PHR proteins f...

Full description

Bibliographic Details
Main Authors: Scott T Baker, Karla J Opperman, Erik D Tulgren, Shane M Turgeon, Willy Bienvenut, Brock Grill
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4014440?pdf=render

Internet

http://europepmc.org/articles/PMC4014440?pdf=render

Similar Items