Distraction of olfactory bulb-medial prefrontal cortex circuit may induce anxiety-like behavior in allergic rhinitis.

Allergic rhinitis is a chronic inflammatory disease of the upper respiratory tract, which is associated with high incidence of anxiety symptom. There is evidence that medial prefrontal cortex modulates anxiety-related behaviors and receives projections from olfactory bulb. Since olfactory dysfunctio...

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Bibliographic Details
Main Authors: Morteza Salimi, Sepideh Ghazvineh, Meysam Zare, Tannaz Parsazadegan, Kolsum Dehdar, Milad Nazari, Javad Mirnajafi-Zadeh, Hamidreza Jamaati, Mohammad Reza Raoufy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221978