Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors

Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors

Alternative polyadenylation (APA) is a widespread mechanism involving about half of the expressed genes, resulting in varying lengths of the 3′ untranslated region (3′UTR). Variations in length and sequence of the 3′UTR may underlie changes of post-transcriptional processing, localization, miRNA tar...

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Bibliographic Details
Main Authors: Elena Grassi, Roberto Santoro, Alessandro Umbach, Anna Grosso, Salvatore Oliviero, Francesco Neri, Luciano Conti, Ugo Ala, Paolo Provero, Ferdinando DiCunto, Giorgio R. Merlo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuron differentiation
GABAergic
polyadenylation
RNA binding protein
Elavl3
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00518/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2018.00518/full

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