Bioactive Tryptophan-Based Copper Complex with Auxiliary β-Carboline Spectacle Potential on Human Breast Cancer Cells: In Vitro and In Vivo Studies

Bioactive Tryptophan-Based Copper Complex with Auxiliary β-Carboline Spectacle Potential on Human Breast Cancer Cells: In Vitro and In Vivo Studies

Biocompatible tryptophan-derived copper (<b>1</b>) and zinc (<b>2</b>) complexes with norharmane (β-carboline) were designed, synthesized, characterized, and evaluated for the potential anticancer activity in vitro and in vivo. The in vitro cytotoxicity of both complexes <...

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Bibliographic Details
Main Authors: Walaa Alharbi, Iftekhar Hassan, Rais Ahmad Khan, Shazia Parveen, Khadijah H. Alharbi, Ibtisam I. Bin Sharfan, Ibrahim M. Alhazza, Hossam Ebaid, Ali Alsalme
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
copper complex
MCF7 cells
MTT assay
ROS
comet assay
in vivo toxicity
Online Access:https://www.mdpi.com/1420-3049/26/6/1606

Internet

https://www.mdpi.com/1420-3049/26/6/1606

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