Targeting Raf Kinase Inhibitory Protein Regulation and Function

Raf Kinase Inhibitory Protein (RKIP) is a highly conserved kinase inhibitor that functions as a metastasis suppressor in a variety of cancers. Since RKIP can reprogram tumor cells to a non-metastatic state by rewiring kinase networks, elucidating the mechanism by which RKIP acts not only reveals mol...

Full description

Bibliographic Details
Main Authors: Ali Ekrem Yesilkanal, Marsha Rich Rosner
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/9/306