Tissue-Specific Microparticles Improve Organoid Microenvironment for Efficient Maturation of Pluripotent Stem-Cell-Derived Hepatocytes

Tissue-Specific Microparticles Improve Organoid Microenvironment for Efficient Maturation of Pluripotent Stem-Cell-Derived Hepatocytes

Liver organoids (LOs) are receiving considerable attention for their potential use in drug screening, disease modeling, and transplantable constructs. Hepatocytes, as the key component of LOs, are isolated from the liver or differentiated from pluripotent stem cells (PSCs). PSC-derived hepatocytes a...

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Bibliographic Details
Main Authors: Ensieh Zahmatkesh, Mohammad Hossein Ghanian, Ibrahim Zarkesh, Zahra Farzaneh, Majid Halvaei, Zahra Heydari, Farideh Moeinvaziri, Amnah Othman, Marc Ruoß, Abbas Piryaei, Roberto Gramignoli, Saeed Yakhkeshi, Andreas Nüssler, Mustapha Najimi, Hossein Baharvand, Massoud Vosough
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
liver organoid
tissue-specific microparticle
pluripotent stem cell
hepatic differentiation
tissue engineering
Online Access:https://www.mdpi.com/2073-4409/10/6/1274

Internet

https://www.mdpi.com/2073-4409/10/6/1274

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