Understanding Zika Virus Stability and Developing a Chimeric Vaccine through Functional Analysis

Compared with other flaviviruses, Zika virus (ZIKV) is uniquely associated with congenital diseases in pregnant women. One recent study reported that (i) ZIKV has higher thermostability than dengue virus (DENV [a flavivirus closely related to ZIKV]), which might contribute to the disease outcome; (i...

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Bibliographic Details
Main Authors: Xuping Xie, Yujiao Yang, Antonio E. Muruato, Jing Zou, Chao Shan, Bruno T. D. Nunes, Daniele B. A. Medeiros, Pedro F. C. Vasconcelos, Scott C. Weaver, Shannan L. Rossi, Pei-Yong Shi, W. Ian Lipkin
Format: Article
Language:English
Published: American Society for Microbiology 2017-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/1/e02134-16