Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivo.

Despite insights into the molecular pathways regulating hypoxia-induced gene expression, it is not known which cell types accomplish oxygen sensing during neo-vasculogenesis. We have developed a humanized mouse model of endothelial and mesenchymal progenitor co-transplantation to delineate the cellu...

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Bibliographic Details
Main Authors: Nicole A Hofmann, Anna Ortner, Rodrigo O Jacamo, Andreas Reinisch, Katharina Schallmoser, Rokhsareh Rohban, Nathalie Etchart, Margareta Fruehwirth, Christine Beham-Schmid, Michael Andreeff, Dirk Strunk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22970226/?tool=EBI