Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

Effects of the surface charge of polyamidoamine dendrimers on cellular exocytosis and the exocytosis mechanism in multidrug-resistant breast cancer cells

Abstract Background Polyamidoamine (PAMAM) dendrimer applications have extended from tumor cells to multidrug-resistant tumor cells. However, their transportation in multidrug-resistant tumor cells remains unclear. Herein, we investigated the exocytosis rule and mechanism of PAMAM dendrimers in mult...

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Bibliographic Details
Main Authors: Jie Zhang, Mingjuan Li, Mingyue Wang, Hang Xu, Zhuoxiang Wang, Yue Li, Baoyue Ding, Jianqing Gao
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Nanobiotechnology
Subjects:
Surface charge
Exocytosis dynamics
Exocytosis pathways
ATP binding cassette proteins
Organelles
Major vault protein
Online Access:https://doi.org/10.1186/s12951-021-00881-w

Internet

https://doi.org/10.1186/s12951-021-00881-w

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