Thiol-Activated Hydrogen Sulfide Donors Antiviral and Anti-Inflammatory Activity in Respiratory Syncytial Virus Infection

Thiol-Activated Hydrogen Sulfide Donors Antiviral and Anti-Inflammatory Activity in Respiratory Syncytial Virus Infection

We have recently shown that endogenous hydrogen sulfide (H2S), an important cellular gaseous mediator, exerts an antiviral and anti-inflammatory activity in vitro and in vivo, and that exogenous H2S delivered via the synthetic H2S-releasing compound GYY4137 also has similar properties. In this study...

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Bibliographic Details
Main Authors: Nikolay Bazhanov, Teodora Ivanciuc, Haotian Wu, Matteo Garofalo, Jianming Kang, Ming Xian, Antonella Casola
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Viruses
Subjects:
respiratory syncytial virus
hydrogen sulfide donor
airway inflammation
mouse model
Online Access:http://www.mdpi.com/1999-4915/10/5/249

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http://www.mdpi.com/1999-4915/10/5/249

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