Surrogate Endpoint Evaluation: Principal Stratification Criteria and the Prentice Definition

A common problem of interest within a randomized clinical trial is the evaluation of an inexpensive response endpoint as a valid surrogate endpoint for a clinical endpoint, where a chief purpose of a valid surrogate is to provide a way to make correct inferences on clinical treatment effects in futu...

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Bibliographic Details
Main Authors: Gilbert Peter B., Gabriel Erin E., Huang Ying, Chan Ivan S.F.
Format: Article
Language:English
Published: De Gruyter 2015-09-01
Series:Journal of Causal Inference
Subjects:
Online Access:https://doi.org/10.1515/jci-2014-0007