Surrogate Endpoint Evaluation: Principal Stratification Criteria and the Prentice Definition
A common problem of interest within a randomized clinical trial is the evaluation of an inexpensive response endpoint as a valid surrogate endpoint for a clinical endpoint, where a chief purpose of a valid surrogate is to provide a way to make correct inferences on clinical treatment effects in futu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
De Gruyter
2015-09-01
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Series: | Journal of Causal Inference |
Subjects: | |
Online Access: | https://doi.org/10.1515/jci-2014-0007 |