Glial tumor necrosis factor alpha (TNFα) generates metaplastic inhibition of spinal learning.

Glial tumor necrosis factor alpha (TNFα) generates metaplastic inhibition of spinal learning.

Injury-induced overexpression of tumor necrosis factor alpha (TNFα) in the spinal cord can induce chronic neuroinflammation and excitotoxicity that ultimately undermines functional recovery. Here we investigate how TNFα might also act to upset spinal function by modulating spinal plasticity. Using a...

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Bibliographic Details
Main Authors: J Russell Huie, Kyle M Baumbauer, Kuan H Lee, Jacqueline C Bresnahan, Michael S Beattie, Adam R Ferguson, James W Grau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3379985?pdf=render

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http://europepmc.org/articles/PMC3379985?pdf=render

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