Gene Transactivation and Transrepression in MYC-Driven Cancers

Gene Transactivation and Transrepression in MYC-Driven Cancers

<i>MYC</i> is a proto-oncogene regulating a large number of genes involved in a plethora of cellular functions. Its deregulation results in activation of <i>MYC</i> gene expression and/or an increase in MYC protein stability. <i>MYC</i> overexpression is a hallmar...

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Bibliographic Details
Main Authors: Marika Scafuro, Lucia Capasso, Vincenzo Carafa, Lucia Altucci, Angela Nebbioso
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
MYC
MYC deregulation
MYC-driven cancers
therapy resistance
therapeutic target
epigenetic modulation
Online Access:https://www.mdpi.com/1422-0067/22/7/3458

Internet

https://www.mdpi.com/1422-0067/22/7/3458

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