Effect of methotrexate and doxorubicin cumulative doses on superoxide dismutase levels in childhood acute lymphoblastic leukemia
Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. Chemotherapeutic drugs for ALL such as methotrexate (Mtx) and doxorubicin produce reactive oxygen species (ROS), a type of free radical. The ROS can reduce levels of antioxidants in the body, including superoxid...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Indonesian Pediatric Society Publishing House
2015-10-01
|
Series: | Paediatrica Indonesiana |
Subjects: | |
Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/42 |