An interferon response gene signature is associated with the therapeutic response of hepatitis C patients.

An interferon response gene signature is associated with the therapeutic response of hepatitis C patients.

Infection with the hepatitis C virus (HCV) is a major cause of chronic liver diseases and hepatocellular carcinoma worldwide, and thus represents a significant public health problem. The type I interferon (IFN), IFNα, has been successful in treating HCV-infected patients, but current IFN-based treat...

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Bibliographic Details
Main Authors: Lawrence M Pfeffer, Kui Li, Jaquelyn F Fleckenstein, Tony N Marion, Joel Diament, Chuan He Yang, Susan R Pfeffer, Meiyun Fan, Elizabeth Handorf, Charles R Handorf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4128657?pdf=render

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http://europepmc.org/articles/PMC4128657?pdf=render

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