Genetic Therapy for Intervertebral Disc Degeneration

Genetic Therapy for Intervertebral Disc Degeneration

Intervertebral disc (IVD) degeneration can cause chronic lower back pain (LBP), leading to disability. Despite significant advances in the treatment of discogenic LBP, the limitations of current treatments have sparked interest in biological approaches, including growth factor and stem cell injectio...

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Bibliographic Details
Main Authors: Eun Ji Roh, Anjani Darai, Jae Won Kyung, Hyemin Choi, Su Yeon Kwon, Basanta Bhujel, Kyoung Tae Kim, Inbo Han
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
genetic therapy
intervertebral disc degeneration
RNAi
mTOR signaling
CRISPR-Cas9
vector
Online Access:https://www.mdpi.com/1422-0067/22/4/1579

Internet

https://www.mdpi.com/1422-0067/22/4/1579

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