Busulfan administration flexibility increases the applicability of scid repopulating cell assay in NSG mouse model.

Busulfan administration flexibility increases the applicability of scid repopulating cell assay in NSG mouse model.

BACKGROUND: Xenotransplantation models allowing the identification and quantification of human Hematopoietic stem cells (HSC) in immunodeficient mice remain the only way to appropriately address human HSC function despite the recent progress in phenotypic characterization. However, these in vivo exp...

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Bibliographic Details
Main Authors: Jean Chevaleyre, Pascale Duchez, Laura Rodriguez, Marija Vlaski, Arnaud Villacreces, Véronique Conrad-Lapostolle, Vincent Praloran, Zoran Ivanovic, Philippe Brunet de la Grange
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3775811?pdf=render

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http://europepmc.org/articles/PMC3775811?pdf=render

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