CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ

CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ

In atherosclerotic plaques, transformation of macrophages into foam cells is a key step in initiating the inflammatory response. Here Fan et al. show that casein kinase 2-interacting protein-1 (CKIP-1) limits foam cell formation and atherosclerosis by preventing expression of the scavenger receptor...

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Bibliographic Details
Main Authors: Jiao Fan, Lifeng Liu, Qingyan Liu, Yu Cui, Binwei Yao, Minghua Zhang, Yabing Gao, Yesheng Fu, Hongmiao Dai, Jingkun Pan, Ya Qiu, Cui Hua Liu, Fuchu He, Yu Wang, Lingqiang Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07895-3

Internet

https://doi.org/10.1038/s41467-018-07895-3

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