The Role of the Vagus Nerve: Modulation of the Inflammatory Reaction in Murine Polymicrobial Sepsis

The particular importance of the vagus nerve for the pathophysiology of peritonitis becomes more and more apparent. In this work we provide evidence for the vagal modulation of inflammation in the murine model of colon ascendens stent peritonitis (CASP). Vagotomy significantly increases mortality in...

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Main Authors: Wolfram Kessler, Stephan Diedrich, Pia Menges, Tobias Ebker, Michael Nielson, Lars Ivo Partecke, Tobias Traeger, Katharina Cziupka, Julia van der Linde, Ralf Puls, Alexandra Busemann, Claus-Dieter Heidecke, Stefan Maier
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2012/467620