Why is NMNAT Protective against Neuronal Cell Death and Axon Degeneration, but Inhibitory of Axon Regeneration?
Nicotinamide mononucleotide adenylyltransferase (NMNAT), a key enzyme for NAD<sup>+</sup> synthesis, is well known for its activity in neuronal survival and attenuation of Wallerian degeneration. Recent investigations in invertebrate models have, however, revealed that NMNAT activity neg...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-03-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/8/3/267 |