Dosage Compensation and Gene Expression of the X Chromosome in Sheep

Dosage Compensation and Gene Expression of the X Chromosome in Sheep

Ohno’s hypothesis predicts that the expression of the single X chromosome in males needs compensatory upregulation to balance its dosage with that of the diploid autosomes. Additionally, X chromosome inactivation ensures that quadruple expression of the two X chromosomes is avoided in females. These...

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Bibliographic Details
Main Authors: Jingyue (Ellie) Duan, Kaleigh Flock, Nathanial Jue, Mingyuan Zhang, Amanda Jones, Sahar Al Seesi, Ion Mandoiu, Sambhu Pillai, Maria Hoffman, Rachel O’Neill, Steven Zinn, Kristen Govoni, Sarah Reed, Hesheng Jiang, Zongliang (Carl) Jiang, Xiuchun (Cindy) Tian
Format: Article
Language:English
Published: Oxford University Press 2019-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Ohno’s hypothesis
X chromosome upregulation
Maternal nutrition
Ovine
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200815

Internet

http://g3journal.org/lookup/doi/10.1534/g3.118.200815

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