Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation
In previous studies the authors discovered that miR-214 inhibits osteoblastic bone formation. Here they extend on these findings, using ovariectomized mice and samples from patients with bone fractures, to show that miR-214 is a mediator of osteoclast-osteoblast crosstalk.
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2016-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms10872 |