KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer

KRAS mutation status concordance between the primary tumor and the corresponding metastasis in patients with rectal cancer

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Introduction Oncogenic mutation within the KRAS gene represents a negative predictor for treatment response to anti-epidermal growth factor receptor (EGFR) in patients with colorectal cancer. Recently, we have shown no relevant heterogeneity for KRAS mutation status within and between pre- and postt...

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Main Authors: Peter Jo, Markus Bernhardt, Manuel Nietert, Alexander König, Azadeh Azizian, Markus A. Schirmer, Marian Grade, Julia Kitz, Kirsten Reuter-Jessen, Michael Ghadimi, Philipp Ströbel, Hans-Ulrich Schildhaus, Jochen Gaedcke, Sumitra Deb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529221/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529221/?tool=EBI

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