Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development

Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development

The ADAMTS family comprises 19 secreted metalloproteinases that cleave extracellular matrix components and have diverse functions in numerous disease and physiological contexts. A number of them remain ‘orphan’ proteases and among them is ADAMTS18, which has been implicated in developmental eye diso...

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Bibliographic Details
Main Authors: Dalya Ataca, Marian Caikovski, Alessandra Piersigilli, Alexandre Moulin, Charaf Benarafa, Sarah E. Earp, Yakir Guri, Corinne Kostic, Yvan Arsenivic, Raija Soininen, Suneel S. Apte, Cathrin Brisken
Format: Article
Language:English
Published: The Company of Biologists 2016-11-01
Series:Biology Open
Subjects:
Adamts18
Metalloproteinase
Lens capsule
Lung development
Vaginal septum
Rete ovary
Online Access:http://bio.biologists.org/content/5/11/1585

Internet

http://bio.biologists.org/content/5/11/1585

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