Genetic Variants in PTGS1 and NOS3 Genes Increase the Risk of Upper Gastrointestinal Bleeding: A Case–Control Study

Genetic Variants in PTGS1 and NOS3 Genes Increase the Risk of Upper Gastrointestinal Bleeding: A Case–Control Study

Objective: To assess the association between PTGS1 and NOS3 variant alleles and the risk to develop upper gastrointestinal bleeding (UGIB) secondary to complicated peptic disease.Methods: A case–control study was conducted in a Brazilian complex hospital from July 2016 to March 2020. Case: Patients...

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Bibliographic Details
Main Authors: Marcela Forgerini, Gustavo Urbano, Tales Rubens de Nadai, Sabrina Setembre Batah, Alexandre Todorovic Fabro, Patrícia de Carvalho Mastroianni
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
drug-related side effects and adverse reactions (MeSH D064420)
genetic polymorphism
peptic ulcer disease
pharmacovigilance (MeSH)
aspirin (MeSH)
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.671835/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.671835/full

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