Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signaling

<p>Abstract</p> <p>Background</p> <p>The physiological regulation of G protein-coupled receptors, through desensitization and internalization, modulates the length of the receptor signal and may influence the development of tolerance and dependence in response to chroni...

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Bibliographic Details
Main Authors: Elliott Heather H, Lieberman Michael D, Scearce-Levie Kimberly, Conklin Bruce R
Format: Article
Language:English
Published: BMC 2005-02-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/3/3