Noninvasive identification of viable cell populations in docetaxel-treated breast tumors using ferritin-based magnetic resonance imaging.

BACKGROUND: Cancer stem cells (CSCs) are highly tumorigenic and are responsible for tumor progression and chemoresistance. Noninvasive imaging methods for the visualization of CSC populations within tumors in vivo will have a considerable impact on the development of new CSC-targeting therapeutics....

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Main Authors: YoonSeok Choi, Hoe Suk Kim, Kyoung-Won Cho, Kyung-Min Lee, Yoon Jung Yi, Sung-Jong Eun, Hyun Jin Kim, Jisu Woo, Seung Hong Choi, Taeg-Keun Whangbo, ChulSoo Choi, Dong-Young Noh, Woo Kyung Moon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534651?pdf=render