ADAM17 silencing in mouse colon carcinoma cells: the effect on tumoricidal cytokines and angiogenesis.

ADAM17 silencing in mouse colon carcinoma cells: the effect on tumoricidal cytokines and angiogenesis.

ADAM17 (a disintegrin and metalloprotease 17) is a major sheddase for numerous growth factors, cytokines, receptors, and cell adhesion molecules and is often overexpressed in malignant cells. It is generally accepted that ADAM17 promotes tumor development via activating growth factors from the EGF f...

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Bibliographic Details
Main Authors: Sudipta Das, Maria Czarnek, Monika Bzowska, Renata Mężyk-Kopeć, Krystyna Stalińska, Barbara Wyroba, Jolanta Sroka, Jarosław Jucha, Dawid Deneka, Paulina Stokłosa, Justyna Ogonek, Melody A Swartz, Zbigniew Madeja, Joanna Bereta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3519469?pdf=render

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http://europepmc.org/articles/PMC3519469?pdf=render

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