Species-, organ- and cell-type-dependent expression of SPARCL1 in human and mouse tissues.

SPARCL1 is a matricellular protein with anti-adhesive, anti-proliferative and anti-tumorigenic functions and is frequently downregulated in tumors such as colorectal carcinoma or non-small cell lung cancer. Studies have identified SPARCL1 as an angiocrine tumor suppressor secreted by tumor vessel en...

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Bibliographic Details
Main Authors: Anika Klingler, Daniela Regensburger, Clara Tenkerian, Nathalie Britzen-Laurent, Arndt Hartmann, Michael Stürzl, Elisabeth Naschberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233422