Poised RNA Polymerase II Changes over Developmental Time and Prepares Genes for Future Expression

Poised RNA polymerase II (Pol II) is predominantly found at developmental control genes and is thought to allow their rapid and synchronous induction in response to extracellular signals. How the recruitment of poised RNA Pol II is regulated during development is not known. By isolating muscle tiss...

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Bibliographic Details
Main Authors: Bjoern Gaertner, Jeff Johnston, Kai Chen, Nina Wallaschek, Ariel Paulson, Alexander S. Garruss, Karin Gaudenz, Bony De Kumar, Robb Krumlauf, Julia Zeitlinger
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124712004214