Plasmacytoid dendritic cells: Development, functions, and role in atherosclerotic inflammation

Plasmacytoid dendritic cells (pDCs) are a specialized subset of DCs that links innate and adaptive immunity. They sense viral and bacterial pathogens and release high levels of Type I interferons (IFN-I) in response to infection. pDCs were shown to contribute to inflammatory responses in the steady...

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Bibliographic Details
Main Authors: Dimitry A Chistiakov, Alexander N Orekhov, Igor A Sobenin, Yuri V Bobryshev
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00279/full