Role of the Death Receptor and Endoplasmic Reticulum Stress Signaling Pathways in Polyphyllin I-Regulated Apoptosis of Human Hepatocellular Carcinoma HepG2 Cells

Polyphyllin has been reported to exhibit anticancer effects against various types of cancer via the proapoptotic signaling pathway. The aim of the present study was to investigate the role of the endoplasmic reticulum stress and death receptor signaling pathways in PPI-induced apoptosis of human hep...

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Bibliographic Details
Main Authors: Qihui Luo, Dandan Yang, Qi Qi, Chao Huang, Bing Chen, Wentao Liu, Liangqin Shi, Yu Xia, Li Tang, Jing Fang, Yangping Ou, Yi Geng, Zhengli Chen
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/5241941