FusionAI: Predicting fusion breakpoint from DNA sequence with deep learning
Summary: Identifying the molecular mechanisms related to genomic breakage is an important goal of cancer mechanism studies. Among diverse locations of structural variants, fusion genes, which have the breakpoints in the gene bodies and are typically identified from the split reads of RNA-seq data, c...
Main Authors: | Pora Kim, Hua Tan, Jiajia Liu, Mengyuan Yang, Xiaobo Zhou |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-10-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004221011329 |
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