α-Defensin HD5 Stabilizes Human Papillomavirus 16 Capsid/Core Interactions

α-Defensin HD5 Stabilizes Human Papillomavirus 16 Capsid/Core Interactions

Background: Human papillomavirus (HPV) is linked to nearly all cases of cervical cancer. Despite available vaccines, a deeper understanding of the immune response to HPV is needed. Human α-defensin 5 (HD5), an innate immune effector peptide, blocks infection of multiple serotypes of HPV, including...

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Bibliographic Details
Main Authors: Neetu M. Gulati, Masaru Miyagi, Mayim E. Wiens, Jason G. Smith, Phoebe Stewart
Format: Article
Language:English
Published: Case Western Reserve University 2019-09-01
Series:Pathogens and Immunity
Subjects:
alpha-Defensins
Human papillomavirus 16
Cryo-electron Microscopy
Mass Spectrometry
Molecular Dynamics
Intrinsically Disordered Proteins
Virus Host Interactions
Online Access:https://paijournal.com/index.php/paijournal/article/view/314

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https://paijournal.com/index.php/paijournal/article/view/314

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