Licensing Natural Killers for Antiviral Immunity

Immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors (IRs) enable discrimination between self- and non-self molecules on the surface of host target cells. In this regard, they have a vital role in self-tolerance through binding and activating intracellular tyrosine phosphatases wh...

Full description

Bibliographic Details
Main Authors: John M. Cronk, Eleni Fafoutis, Michael G. Brown
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/7/908