NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells

NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells

The differentiation of naïve CD4+ T cells into T helper (Th) subsets is key for a functional immune response and has to be tightly controlled by transcriptional and epigenetic processes. However, the function of cofactors that connect gene-specific transcription factors with repressive chromatin-mod...

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Bibliographic Details
Main Authors: Daniela Hainberger, Valentina Stolz, Ci Zhu, Michael Schuster, Lena Müller, Patricia Hamminger, Ramona Rica, Darina Waltenberger, Marlis Alteneder, Thomas Krausgruber, Anastasiya Hladik, Sylvia Knapp, Christoph Bock, Michael Trauner, Michael A. Farrar, Wilfried Ellmeier
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
NCOR1
corepressor
CD4+ T cells
T helper differentiation
colitis
interferon γ
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00579/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00579/full

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