Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C

Generation of Transgenic Mice that Conditionally Overexpress Tenascin-C

Tenascin-C (TNC) is an extracellular matrix glycoprotein that is expressed during embryogenesis. It is not expressed in normal adults, but is up-regulated under pathological conditions. Although TNC knockout mice do not show a distinct phenotype, analyses of disease models using TNC knockout mice co...

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Bibliographic Details
Main Authors: Saori Yonebayashi, Kazuko Tajiri, Mari Hara, Hiromitsu Saito, Noboru Suzuki, Satoshi Sakai, Taizo Kimura, Akira Sato, Akiyo Sekimoto, Satoshi Fujita, Ryuji Okamoto, Robert J. Schwartz, Toshimichi Yoshida, Kyoko Imanaka-Yoshida
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
matricellular protein
Cre-Lox
Atp8a2
heart development
myocardial inafrction
Nkx2.5
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.620541/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.620541/full

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