Profilin2 regulates actin rod assembly in neuronal cells

Abstract Nuclear and cytoplasmic actin-cofilin rods are formed transiently under stress conditions to reduce actin filament turnover and ATP hydrolysis. The persistence of these structures has been implicated in disease pathology of several neurological disorders. Recently, the presence of actin rod...

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Bibliographic Details
Main Authors: Lisa Marie Walter, Sebastian Rademacher, Andreas Pich, Peter Claus
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-89397-9