Cytotoxic, clastogenic and genotoxic effects of cis-tetraammine(oxalato)ruthenium(III) dithionate on human peripheral blood lymphocytes

Cytotoxic, clastogenic and genotoxic effects of cis-tetraammine(oxalato)ruthenium(III) dithionate on human peripheral blood lymphocytes

There is a concern about stablishing the clinical risk of drugs used for cancer treatment. In this study, the cytotoxic, clastogenic and genotoxic properties of cis-tetraammine(oxalato)ruthenium(III) dithionite - cis-[Ru(C2O4)(NH3)4]2(S2O6), were evaluated in vitro in human lymphocytes. The mitotic...

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Bibliographic Details
Main Authors: Manuela da Rocha Matos Rezende, Vivianne de Souza Velozo-Sá, Cesar Augusto Sam Tiago Vilanova-Costa, Elisangela Silveira-Lacerda
Format: Article
Language:English
Published: Universidade Estadual de Maringá 2020-05-01
Series:Acta Scientiarum : Biological Sciences
Subjects:
ruthenium complexes; mitotic index; chromosomal aberrations; comet assay.
Online Access:http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/50517

Internet

http://www.periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/50517

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