Histological, immunohistochemical and transcriptomic characterization of human tracheoesophageal fistulas.

Esophageal atresia (EA) and tracheoesophageal fistula (TEF) are relatively frequently occurring foregut malformations. EA/TEF is thought to have a strong genetic component. Not much is known regarding the biological processes disturbed or which cell type is affected in patients. This hampers the det...

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Main Authors: Erwin Brosens, Janine F Felix, Anne Boerema-de Munck, Elisabeth M de Jong, Elisabeth M Lodder, Sigrid Swagemakers, Marjon Buscop-van Kempen, Ronald R de Krijger, Rene M H Wijnen, Wilfred F J van IJcken, Peter van der Spek, Annelies de Klein, Dick Tibboel, Robbert J Rottier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242167